That depends which side of the agri-corporate/military-industrial food chain you are on. Monsanto at it’s roots is a ruthless company that has taken no prisoners and done all it can to subvert food production to it’s own profit. As a farmer for many many years I’ve seen it first hand - the legal team of Monsanto is a fearful device.
Part of the issue with modern north america wheat is twofold - it was crossed with a grass which has brought the size of the plant down, increased yields and made it easier to manage in an industrial process, however it has potentially introduced issues with reactions - I agree it is not the gluten intolerance - it is the other things we have added to the wheat. Wheat today is not the wheat of our ancestors. It is no longer the 'golden staff of life". The second issue with north american wheat is that it is generally desiccated with Roundup pre-harvest to kill the plant, which allows for an easier harvest, harder kernels etc. It seems that there is increasing evidence that what people think of as gluten intolerance is more likely to be a herbicide or other additions.
GMO’s have been primarily field tested on the populace of north america over the last 20 years. The consumers are the lab rats.