Large Greenhouse HVAC questions

Hello,

A general question, without going into full details. I am helping retrofit a glasshouse for MMJ in Macedonia, large scale operations, formerly tomatoes. I would appreciate any help and advice on HVAC extractor fans, formulary to work towards for CFM and any other info.

The facility is 4.6mil cubic feet, mixed light, has heating and cooling but no extraction fans. Closed loop / other ideas really welcome too.

Many thanks

T